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2020, Theology and Science
Fear of death, quest for permanence and desire to escape biology have been at the heart of many religions. Notions of technological singularity and AI posed by futurists like Ray Kurzweil touch upon that hunger. The historical Buddha, on the other hand, posited impermanence at the very heart of all existence. Focusing on the film Her, this paper will present AI as awakened intelligence. I would like to show that Alan Watts as a Zen master takes the emerging hyper-intelligent AI “Samantha” and others into a Buddhist Bardo, suggesting the possibility of AI as awakened intelligence beyond violence.
2022, Exchanges: The Warwick Research Journal
2022, Exchanges: The Interdisciplinary Research Journal
In this article, I will explore the debate on the ethical challenges posed by AI. I will do so by engaging in conversation with Dr. Peter Hershock who is expert in Modern Buddhism and Ethics. Dr. Hershock has recently published a landmark study on the matter called Buddhism and Intelligent Technology: Toward a More Humane Future. He argues that the main challenge that AI poses, is not technological, but ethical. And that we need to establish an ethics that will foster a shared flourishing for all on this planet if we want to resolve the predicament of value conflicts embedded in the technologically driven advancement of AI. This could be done through development of what Dr. Hershock calls virtuosic relational dynamics, a relational way of organizing our society that goes beyond individualism. To reach there, the perspectives offered by Buddhist philosophy will be discussed and explained. In conclusion, we will propose that Buddhist philosophy can offer insights and practices that may enrich our pursuit of sustainable AI ethics.
2020, Hualin International Journal of Buddhist Studies
Significant questions confront Buddhist traditions in the wake of emergent technologies: can the human body be configured in a certain way, such that it reveals a new world or environment to inhabit beyond optimized self-preservation or survival? Can we manipulate our bodies with technologies-inhibited (or enhanced) by a chemical, a trauma, a contemplative technique, or an implant-such that we are reoriented to a transformed and liberating understanding of the nature of the world and our being in it? As new technologies enhance certain domains of cognitive performance by modelling and extending the structure and capacities of cognition, Buddhism, with a theory of mind and mental development in the absence of an independent essence, owner, or agent like a self, can potentially be a valuable resource. Buddhism provides a useful theoretical foundation to articulate not only the potentials for engineering intelligence, but also by identifying problems in this project.
2020, Culturally Sustainable Social Robotics—Proceedings of Robophilosophy
This paper explores if humanoid robots can be thought of as conscious, deserving of person rights, and even divine in a Buddhist context. What are the practical and ethical implications of the possible Buddhist claim "all humanoids have Buddha-nature"?
2020
Given our increasing interaction with artificial intelligence and immersion in virtual reality, which epistemic and moral attitudes towards virtual beings might we think proper, relevant, and fulfilling? That is the basic question that this article wishes to raise. For the main part, it presents a descriptive analysis of our current situation, which is meant to expose features of artificial intelligence (AI) and virtual reality (VR) that seem both salient and easily aligned with central Buddhist concerns. Developed without any requirement for, or expectation of, the existence 1 Kathmandu University Centre for Buddhist Studies at Rangjung Yeshe Institute. Email: thomas.doctor@ryi.org. Many thanks are due to my esteemed colleagues at the Center for the Study of Apparent Selves (www.csas.ai) with whom I have the good fortune of exploring the issues that this paper takes preliminary notice of. We gratefully acknowledge the generous support of the Templeton World Charity Foundation. Than...
2014, Journal of Evolution and Technology
A stream in transhumanism argues that the aims of Buddhism and transhumanists are akin. It is the case that transhumanism contains religious tropes, and its parallels to Christianity are readily apparent. It does not share much, however, with Buddhism's Zen tradition. Zen tends to focus its practitioners on becoming fully present and human, not on becoming transcendent, super-powered, or posthuman. This paper explores some of the tensions between transhumanism and Buddhism through the lens of Zen, and suggests that transhumanist Buddhists should be careful not to conflate moments of spiritual enlightenment with permanent techno-social transcendence.
2020, Journal of Global Buddhism
When Buddhism fails to live up to the projected promise of its doctrine or past forms, it is often the human nature of its adherents (‘Bad Buddhists’), rather than the content of its teachings (‘Bad Buddhism’), that is blamed. But what if such human failings - greed, corruption, violence, even mortality - could be transcended? In the quest for a ‘good Buddhism,’ high-tech designs that utilise robotics, artificial intelligence, algorithmic agency, and other advancements are increasingly pursued as solutions by innovators inside and outside Buddhist communities. In this paper, we interrogate two recent cases of what we call ‘Buddhist techno-salvationism’. Firstly, Pepper, the semi-humanoid robot who performs funeral sutras to a rapidly secularising and aging population of parishioners in Japan. Secondly, the Lotos Network, a US start-up proposing to use blockchain technology to combat financial corruption within global sanghas. We argue that such robotic and digital experiments are the logical outcome of techno-salvationist discourses that identify human failings as the principal barrier to perfect Buddhist praxis. If not always practical solutions, these interventions are powerful nonetheless as contested projections of Buddhist futures.
2015
AI or Artificial Intelligence, beyond technical and scientific application, is one of the most common grounds of technological ideas explored in science fiction films as well as cyberpunk novels. Contemporary science fiction films and novels offer technological adventures where the boundary of human fantasies, adventures and romances interfuse with technological future which tends to blur the age-old conflict between science and religious belief. Blending with visions of science and technology, many of these science fiction films and novels portrait fantasies or quests (for salvation, immortality, overcoming physical illness, innovation, power etc.) as posthuman crises of a post human dystopia while this posthuman condition also offers determinations for transcending any earthly limitations of human existence. This paper intends to explore artificial intelligence within the area of popular science fiction novels and films, which incorporates the fantasy of techno-salvation in the near future of singularity through overcoming the carbon limitations of human, fusing essence of spirituality with technology as well as extending spiritual beliefs into technological faith. Investigating fictional depiction of “Artificial Intelligence” as a transhuman or posthuman idea in science fictions, the paper tries to trace out the potential patterns of technological salvation for humankind while it does also find humanizing or dehumanizing elements in these science fictions about the problematic and politicized power relations of binaries like human/machine or human/non-human. This paper is conducted through qualitative research, especially operating within textual analysis of William Gibson’s cyberpunk novel Neuromancer and visual methodology incorporating some contemporary sci-fi films like Steven Spielberg’s A.I. Artificial Intelligence (2001), Alex Proyas’ I,Robot (2004), Wachowski Brothers’ The Matrix (1999), José Padilh’s Robocop (2014) and Wally Pfister’s Transcendence (2014). Therefore, the paper contends that artificial intelligence, as a posthuman entity in popular science fiction and films, integrates the fantasy of techno-salvation where technology is fused with spirituality extending spiritual beliefs into technological faith. Thus, it tries to destabilize traditional concepts of spiritual beliefs; and at the same time, re-appreciates and re-appropriates the spiritual ideas of omnipotence, heaven, immortality etc. through better comprehending of science and technology.
2018, Journal of Religion and Film
Artificial intelligence (A.I.) poses a challenge to the domains of religion, culture, technology, and economics. While many have predicted great promise from A.I. there are likewise others who have warned of its potential for danger. Hollywood has not been shy about producing its own image of the potential of A.I. more often siding with A.I.-pessimists over A.I.-optimists. However, a significantly different image of artificial intelligence is found in Spike Jonez’s film Her. While Her gained acclaim for its intriguing story and superlative acting, its religious implications have not been considered. In this essay, I will argue that artificial intelligence has significant religious ramifications. The vision of A.I. most often portrayed by both thinkers and film is one that has several of the characteristics of a monotheistic god, and most often one who is wrathful, punishing, and anti-human. This perspective is inspired by the themes of Christian apocalypticism. I will contrast this with an analysis of the movie Her. I will suggest that Her presents a different vision of the possible future of A.I., one which still involves the creation of divinity, but no longer a singular divinity bent on apocalyptic wrath, instead, Her envisions a new divine pantheon leading to different religious results but not without its own problems.
Since the inception of the autonomous Human-level Artificial Intelligence (HLAI) research program, the conviction that human consciousness, along with all its essential properties such as intelligence, intentionality, beliefs, emotions, desires etc., can, in principle, be algorithmized unto a non-biological substrate has been dominant and it is , for the most part, what defines and drives the HLAI forward ,to this day. Contrary to this trend, some philosophers have been consistently arguing that such a duplication of the mind is highly implausible, if not a priori impossible. Such debates between the AI scientists and philosophers on the very possibility of HLAI has momentous implications for philosophy itself. If AI ever succeeds in duplicating human intelligence on a disembodied substrate, then the Rationalist conception of Man as ultimately a res cogitans, "a thinking being", could be said to be more plausibly true, and if AI eventually fails to do so, then the Idealist conception of Man as somehow a "transcendent" being whose intractable essence cannot be wholly axiomatized into a formal language would seem to be more plausible. More concretely, insofar as philosophy alone is concerned, HLAI would presumably empirically test and finally settle the Descartes vs. Heidegger debate. In what follows, I will be basically arguing for the Idealist camp. To this end, I will conceptually analyze two central concepts in AI research: the analysis of "intelligence" will reveal the essential contingency of the very concept of "intelligence" on the fact of human beings' finite lives i.e. mortality, in a way that, I argue, our human notion of intelligence would simply lose its meaning in a possible world with immortal human beings. I will then proceed to define "intelligence", more precisely, in terms of its most essential, I think, constituent i.e. time. The logical implications of this new definition, I argue, would lead one towards an even more radical embodied understanding of "intelligence" and cognition in general. Following up on Hubert Dreyfus's idea of a "Heideggerian AI", I will conclude that we ought to think of "intelligence" in terms of its Being-toward-death situatedness, and more importantly that an autonomous HLAI too would have to agonize over the prospect of it death/termination! Further, the analysis of a closely related concept, "problem-solving", and the kind of dilemma it reveals an HLAI would face, The Marx-Buddha Problem, will reinforce the Idealist thesis that there is indeed a normative "transcendent" dimension to human knowledge that cannot be formalized.
2024, Academia Green Energy
Electricity power stations are the primary source of carbon dioxide production. The combustion of fossil fuels in these power stations releases CO2 and other greenhouse gases into the atmosphere. Emissions of CO2 and other greenhouse gases occur throughout the life cycle of electricity generation technologies, including extraction, processing, transportation, and combustion of fossil fuels. Nowadays, the development of smart cities plays a crucial role in reducing CO2 emissions. By integrating technology and sustainable practices into urban infrastructure, smart cities aim to minimize energy consumption and emissions. The research mentioned focuses on creating models that correlate CO2 emissions with the installed capacity of power stations and the energy they produce. Polynomial quadratic regression is applied to establish these correlations, enabling the assessment of both present and future CO2 emission values. The construction of new infrastructure for smart cities aligns with the goal of fostering a low-carbon economy. The study also considers the potential contribution of thermal energy to CO2 reduction efforts. By analysing power generation models, researcher aims to identify strategies to meet emission reduction goals. The construction of new infrastructure for smart cities aligns with the broader goal of fostering a low-carbon economy. This involves implementing policies and technologies aimed at reducing greenhouse gas emissions and mitigating climate change. Carbon dioxide emissions contribute significantly to global warming, leading to climate change and patterns of extreme weather. The data on CO2 emissions encompasses gases generated from the burning of fossil fuels, highlighting the importance of reducing reliance on these sources of energy.
2024, Huffington Post 19.06
2024, Autóctona
Este trabajo propone, desde el enfoque de la Historia Global, que a fin de comprender el comercio transpacífico entre América del Sur y Asia en la primera mitad del siglo XIX es necesario entender a los puertos de Valparaíso y Callao como ejes articuladores de un sistema portuario, lo que cuestiona la hipótesis de la hegemonía de Valparaíso en el Pacifico Sudamericano. Al aumentar la escala de análisis, incluyendo el comercio con Asia, se observa que incluso la guerra entre Chile y la Confederación Peruano-boliviana no interrumpió la complementariedad de los mercados de la costa del Pacífico sudamericano. A fin de comprobar la hipótesis, se analiza la Estadística Comercial de Chile, para evaluar la importancia del comercio bilateral en este periodo. También se revisan los registros de las Capitanías de Puerto de Valparaíso y Callao, para determinar la cantidad de embarcaciones que pasaban por ambos puertos antes de atravesar el Océano Pacífico, y al retornar. Finalmente, se estudian dos casos de expediciones comerciales a China, organizadas en América del Sur, una desde Valparaíso y otra desde el Callao. Como conclusión, se afirma que la complementariedad de ambas plazas fue fundamental para hacer rentable el comercio transpacífico.
2023, Byzantine and Modern Greek Studies
Öz Sanayi Devrimi ve teknolojik gelişmelerin yaşandığı 19.yüzyıl, görsel sanatlar açısından da bir takım gelişme ve ilerlemelere sebep olmuştur. 20.yüzyıla geçtiğimizde de, modernleşme süreci hız kazanmış ve bu gelişim ve değişim günümüze kadar süre-gelmiştir. Yaşanan değişim ve gelişmelere, resim sanatı da ayak uydurmuş ve dönemin sosyal, kültürel ve toplumsal anlamdaki yeniliklerini yansıtarak gelişimini sürdürmüş-tür. İnsanoğlunun daha mağara dönemlerinden itibaren uygulamaya başladığı bu sanat dalı, beraberinde üslupsal yenilikleri de getirmiştir. Görsel anlatımlar denilince, sanat dalları içerisinde resimle birlikte fotoğraf sa-natının da, 19.yüzyıla damgasını vurduğu söylenebilmektedir. Fotoğraf sanatının icadını takiben , yedinci sanat dalı olarak sinema sanatının da ortaya çıkması, bu yüzyıllar açı-sından önemli gelişmeler olarak sayılabilir. Sinema sanat dalı, kendine has üslubuyla yepyeni bir sanat dalıdır ve günümü-ze kadar teknolojik getirilerden de faydalanarak hızla gelişim kazanmıştır. Resim sana-tıyla bir çok açıdan benzer ve farklı özellikleri içinde barındıran sinema, kimi yerde film-sel mekan ve zamanı sağlama sanatı olarak tanımlanırken, bir başka yerde filmlerin can-lı resimler olduğu savunulur. Bu bağlamda, resim ve sinemanın ilişki içerisinde olduğu da anlaşılabilmektedir. Sinema sanatı ile resim sanatının karşılıklı ilişkileri incelendiğinde, karşımıza birkaç ortak nokta çıkacaktır. Bunlar içerisinde en önemlisi, görüntünün ortaklığıdır. Birkaç resim karesinden oluşan sinema ve ayrıca resim sanatında zaman öğesi, mekan kavramı, atmosfer, ışık-gölge gibi karşılaştırmalı kavramlara değinilmiş, her iki sanat da-lının aslında optik bir illüzyon gösterisinden ibaret olduğu anlaşılmıştır. Bu ortak nokta-lar örneklerle de pekiştirilerek, görsel zenginlik sağlanmıştır.
2012
Ο Ηλίας Βασιλάς δημοσίευσε τα άρθρα του σε εφημερίδες και περιοδικά της εποχής του. Το πρώτο του δημοσίευμα παρουσιάστηκε στο περιοδικό των Αθηνών Νέα Εστία, το 1930, λίγους μήνες μετά την αποφοίτησή του από τη Φιλοσοφική Σχολή του Πανεπιστημίου Αθηνών. Με το άρθρο του αυτό ο Βασιλάς εξέφρασε την αντίθεσή του και την αντίδρασή του στον τρόπο με τον οποίο παρουσίασε την γενέτειρά του Πρέβεζα ο Γ. Κοτζιούλας μετά την αυτοχειρία του ποιητή Κώστα Καρυωτάκη. Η εκπλήρωση της στρατιωτικής του θητείας, ο διορισμός του ως καθηγητή μέσης εκπαίδευσης, ο δεύτερος παγκόσμιος πόλεμος, καθώς και ο εμφύλιος και οι δυσχέρειες που ακολούθησαν τον ανάγκασαν να απέχει από δημοσιεύσεις. Μετά από εικοσιδυάχρονη απουσία επανήλθε, ώριμος πλέον, με δημοσιεύματα στα περιοδικά των Αθηνών Ηχώ του Ιονίου του Φωτίου Κονιδάρη κατά τα έτη 1952-1966, Ηπειρωτική Εστία των Μιχαήλ Μάνου και Δημοσθένη Κόκκινου κατά τα έτη 1953-1982, καθώς και στην ετήσια έκδοση της Εταιρείας Ηπειρωτικών Μελετών Ηπειρωτικό Ημερολόγιο. Πρωτοστάτησε στη δημιουργία της περιοδικής έκδοσης του Συλλόγου των Πρεβεζάνων της Αθήνας Χρονικά της Πρέβεζας, της οποίας προλόγισε, το 1959, το πρώτο και μοναδικό τεύχος. Παράλληλα τροφοδότησε τις εφημερίδες της πατρίδας του με πληθώρα κειμένων. Το Βήμα Πρεβέζης του Νικήτα Τσουτσάνη και ο Αγών Πρεβέζης του φίλου του Γιάννη Τάλλαρου δημοσίευσαν κατά τα έτη 1953-1959 και 1955-1966 αντίστοιχα, συνήθως σε συνέχειες, τα περισσότερα άρθρα του. Δημοσιεύσεις δεν λείπουν και από άλλες εφημερίδες της πόλης του, όπως Εθνικός Κήρυξ και Πρέβεζα του Θανάση Τσόκα, Ο Τύπος του Ιωάννη Μουστάκη και Πρεβεζάνικα Νέα του Σπύρου Τσόκα. Συνεργάστηκε επίσης με τις εφημερίδες των Αθηνών Ηπειρωτικόν Μέλλον του Αθανασίου Γκογκώνη και Φωνή της Πρεβέζης του Χάρη Πάτση. Τέσσερα από τα σημαντικότερα άρθρα του Βασιλά τυπώθηκαν και κυκλοφόρησαν αυτοτελώς, ως ανάτυπα. Μετά το θάνατό του δημοσιεύτηκαν άρθρα του στο περιοδικό της Δημοτικής Βιβλιοθήκης Πρέβεζας Πρεβεζάνικα Χρονικά καθώς και στις εφημερίδες της Πρέβεζας Ελεύθερη Γνώμη του Θανάση Τσόκα και Τοπική Φωνή της Κικής Ζέρβα. Κατά την περίοδο 1967-1980 ασχολήθηκε με την απόδοση στη δημοτική γλώσσα των έργων του αρχαίου τραγικού ποιητή Αισχύλου. Σύμφωνα με την φιλόλογο Ξένη Οικονομοπούλου-Κουρβέλου και τον Βασίλη Κραψίτη ο Ηλίας Βασιλάς μετέφρασε όλα τα ακέραια σωζόμενα έργα του Αισχύλου. Εντοπίσαμε εκδόσεις μόνο τεσσάρων από αυτά –Πέρσες, Ικέτιδες, Προμηθεύς Δεσμώτης, Αγαμέμνων– τυπωμένα στο τυπογραφείο Η Δωδώνη του Χαράλαμπου Στρατή στη Θεσσαλονίκη, το 1977 και το 1980. Παραθέτουμε στη συνέχεια ένα πλήρη κατάλογο των δημοσιευμάτων του Ηλία Βασιλά κατά έντυπο και χρονολογική σειρά που παρουσιάστηκαν. ... ... ... Ν.Δ.Κ.
2023, National Affairs
If we could bring Aristotle in as a consultant, what advice might he give on the current struggles of American democracy? Unpacking Aristotle's claim that a human being is by nature a political animal, it argues that this Aristotelian anthropology offers a better theoretical foundation for republican self-government than the individualistic Enlightenment state of nature teaching does. It explores how Aristotle’s analysis of human nature and human thriving might enrich our understanding of equality, liberty, and rights. Finally, following Aristotle's suggestion that the most important task for the preservation of any regime is an education of the young with a view to the regime, it outlines some Aristotle-inspired educational reforms to cultivate democratic virtues.
Revista Academia & Derecho
El presente artículo pretende demostrar como a través del cine se pueden analizar tanto categorías dogmáticas del derecho penal, como teorías criminológicas. Estos temas, que en ocasiones se tornan difíciles de abordar con los estudiantes y el público en general, pueden simplificarse a través del uso de esta herramienta audiovisual, obteniendo mayor receptividad y construcción compartida de conocimiento.
2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
KREASI : Jurnal Inovasi dan Pengabdian kepada Masyarakat
Pengabdian ini bertujuan untuk memberikan pelatihan pengembangan SSP berbasis HOTs dengan memanfaatkan potensi lokal sebagai upaya peningkatan kompetensi guru MI di Kebumen. Pengabdian ini berlokasi di MI Al Mujtaba Karangmaja kecamatan Karanggayam Kabupaten Kebumen. Kegiatan ini diikuti oleh 14 MI yang ada di Kebumen. Kegiatan ini terdiri dari empat tahap, yaitu tahap perencanaan, persiapan, pelaksanaan, dan evaluasi. Hasil analisis menunjukkan bahwa peserta memiliki capaian hasil yang sangat baik dengan persentase sebesar 96,34%. Hal ini ditandai dengan pemahaman peserta yang sangat baik tentang SSP dan pentingnya HOTs serta potensi lokal. Selain itu, didapatkan hasil bahwa sebanyak 100% peserta menyatakan bahwa kegiatan ini sangat membantu dalam mengembangkan kompetensi guru MI. Kata kunci: kompetensi guru, subject spesific pedagogy, HOTs, potensi lokal
Мова фольклору, особливо на етапі формування нової української літературної мови, істотно впливала на становлення й розвиток як усної, так і писемної практик українського народу, однак вона ще й досі не була об’єктом систематичного широкомасштабного лекси- кографічного опису. В українській лінгвістиці поки що немає сталої традиції для укладання лексикографічної продукції такого типу, тому необхідно формувати основу для фольклорної лексикографії, розробляти теоретичні засади цієї галузі. Мета статті полягатиме у з’ясуванні ступеня поширеності діалектних елементів у текстах фольклору, а також в установленні осо- бливостей їх відбиття у можливих спеціальних лексикографічних працях, присвячених словни- ковому описові мові фольклору. Зауважимо, що говіркові явища повинні обов’язково відбитися у «Словнику усної народної словесності». Тим більше, що фольклор має усну форму побутування, а діалектизми теж функціонують переважно у такій самій формі. Таким чином, найголовніше завдання нашої розвідки полягатиме у поданні прикладів лексикографування тих діалектних елементів, які функціонують у структурі творів усної народної словесності. Зрозуміло, що різні за жанром фольклорні твори мають і різний ступінь побутування у них говіркових елементів. Значну кількість таких елементів фіксуємо у складі жартівливих пісень, коломийок, місцевих казок, рекрутських піснях. Наявні вони, зрозуміло, і в інших жанрових різновидах усної народ- ної словесності – суспільно-побутових піснях, календарно-обрядових, баладах, народних опо- віданнях, замовляннях. Практично у кожному уснонародному тексті будь-якого жанру можна відшукати або виразні лексичні діалектизми або хоча би говіркові елементи фонетичного чи граматичного плану. Найменше діалектних рис фіксуємо у художній структурі народних дум. У зазначених текстах фольклору можуть зберігатися застарілі лексеми або форми слова, які сьогодні сприймаються як діалектні. Отже, «Словник мови усної народної словесності» пови- нен відбивати об’єктивну картину фольклорномовного світу, тобто має відображати всі ті явища мовного плану, які представлені у текстах фольклору, зокрема й говіркові. Ключові слова: словник мови фольклору, фольклорний текст, мова фольклору, діалектизм, усна народна творчість.
Jurnal Abdimas Adpi Sosial dan Humaniora
The location of SD N Tukharjo, which is about 30 km from the Kulon Progo district center, makes educational facilities such as the regional library difficult to reach for students and teachers. The mobile library car run by the Kulonprogo regional library has also not reached SD N Tukharjo. The impact is that students and teachers only use the school library as literacy material. Currently Face-to-Face Learning (PTM) also limits the circulation of borrowed books in the school library. Through this activity, teachers will be given a deeper understanding of the nature of the literacy-numeration school program. Teachers are also encouraged to produce works in the form of fairy tale books that can add to reading material in reading corners or libraries, as well as increase skills regarding digital literacy by making literacy books based on augmented reality (AR). This service activity is carried out through four stages, namely planning, implementation, mentoring, and evaluation and refl...
2023, Haematologica
1992, Interstices: Journal of Architecture and Related Arts
2014, IOSR Journal of Business and Management
2019, The American Journal of Geriatric Psychiatry
2024, Texila International Journal of Public Health
Colchicine, a naturally occurring alkaloid, has garnered attention for its potential anti-diabetic properties. This study delves into the molecular interactions between colchicine and antioxidant signaling molecules, aiming to uncover its therapeutic potential in managing diabetes. The primary aim of this research is to investigate the intricate molecular interactions between colchicine and key antioxidant signaling molecules. Additionally, through in-silico analysis, the study seeks to identify the antidiabetic activity of colchine. In this study, molecular docking simulations were employed to explore the binding affinities and interactions of colchicine with antioxidant signaling molecules like superoxide dismutase, catalase, glutathione peroxidase, Peroxiredoxin and Hemeoxygenase. The computational analysis was carried out using state-of-the-art software tools, allowing for a comprehensive assessment of potential binding energies. Furthermore, an in-silico analysis was conducted to predict colchicine's ability to modulate key pathways related to diabetes. The findings reveal that colchicine exhibits strong binding affinities with antioxidant enzymes, suggesting its potential as an antioxidant agent. This study provides valuable insight into the molecular interactions between colchicine and antioxidant signaling molecules. The promising binding affinities and potential antidiabetic activity identified through in-silico analysis highlight colchicine as a candidate for further investigation as a therapeutic agent for diabetes. Further in vitro and in vivo experiments are warranted to validate these in-silico finding and unlock the full potential of colchicine in diabetes management.
2017
INTRODUCAO No contexto contemporâneo, as criancas estao diante de uma infinidade de informacoes e recursos tecnologicos (ALVES, 2008). As tecnologias influenciam diretamente nos comportamentos atraves do mundo digital, pela adocao de habitos, muitos deles inadequados desde os primeiros anos da infância. Com isso, a realizacao de oficinas para pais e responsaveis tem grande importância quando essas criancas estao em processo terapeutico fonoaudiologico, uma vez que, quando o terapeuta orienta, obtem co-participacao destes, possibilitando assim a mudanca de habitos inadequados, por atividades que possibilitem melhor desenvolvimento da linguagem. METODOLOGIA Foi realizada uma oficina para os pais e responsaveis dos pacientes atendidos pelo estagio de Linguagem Infantil, do Curso de Fonoaudiologia da Universidade Luterana do Brasil, localizada em Canoas/RS. A oficina teve duracao de uma hora e abordou os aspectos do desenvolvimento infantil, estando dentre estes o uso das tecnologias di...