PROCESS FOR USING METAL/ METAL ALLOY NANOPARTICLES AS NOVEL ANTI-SPROUTING AGENTS
Indian Patent, Application No.1170/CHE/2012, 28th March 2012
The present invention relates to usage of noble metal nanoparticles as novel anti-sprouting agent useful in inhibiting... more The present invention relates to usage of noble metal nanoparticles as novel anti-sprouting agent useful in inhibiting the undesired growth of tuber. More particularly, the invention relates to usage of metal nanoparticles especially silver, gold, platinum, iron and copper nanoparticles which may be used to inhibit tuber sprouting. In addition, the said anti-sprouting agent checks loss of fresh weight, rotting and fungal growth. These particles may be bare or capped or functionalized by one or more organic moieties or by one or more polymers used as anti-sprouting agents in different tuber specific plants.
Process for producing metal nanoparticles from metal salt solutions using milk and milk preparations
Indian Patent,Application No.1494/CHE/2010
This invention claims the process of synthesizing metal nanoparticles using fraction of any form of milk and milk... more This invention claims the process of synthesizing metal nanoparticles using fraction of any form of milk and milk preparations. A process of combining at least one metal salt or one metal cation in dry state or in any form of solution reduced with fraction of any type milk and milk preparations. The claim also includes the any possible reaction condition like heating in ambient temperature, UV irradiations, photo irradiations with natural sunlight, microwave heating, infrared heating for obtaining metal nanoparticles using different milk and milk preparations as reducing medium
Anti-cancer studies of noble metal nanoparticles synthesized using different plant extracts
Published in' Cancer Nanotechnology' Journal.
Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro... more Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro anti-cancer efficacy against four different cancer cell lines human colorectal adenocarcinoma, human kidney, human chronic myelogenous, leukemia, bone marrow, and human cervix have been studied and reported. The present experimental study suggests that flavonoids functionalized gold nanoparticles synthesized using aqueous clove buds extract are more potential than guava leaf extract towards anti-cancer activities. The microscopic and 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assay infer that the functionalized irregular shaped gold nanoparticles synthesized with aqueous clove bud extract showed a satisfactory anti-cancer effect on all the cell lines. The silver nanoparticles synthesized using same extracts are devoid of anti-cancer activity. The XTT assay revealed dose-dependent cytotoxicity to cancer cell lines. The study revealed that the free radicals generated by gold nanoparticles are responsible for anti-cancer effect. To confirm the free-radical scavenging efficacy of gold nanoparticle, nitric oxide assay is followed. We observed that the gold nanoparticles swabbed the free radicals in dose-dependent manner. With continued improvements, these nanoparticles may prove to be potential anti-cancer agents